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Sie sind hier: Startseite Forschung Prof. Dr. H. Häberlein (IBMB assoziiert) Publikationen


Publikationen ab 2004

  • Bussmann H., Häberlein H., Boonen G., Drewe J., Butterweck V. and Franken S. (2022) Effects of St. John´s wort extract Ze 117 on the lateral mobility of β1-adrenergic receptors in C6 cells. Biomed. Pharmacother. Nov 14;157:114006.doi: 10.1016/j.biopha.2022.114006
  • Aatz S., Franken S., Kolb C. and Häberlein H. (2022) St John´s wort extract STW3-VI affects the binding behaviour, signal transduction and lateral mobility of 5-HT2A receptors observed by single molecule detection and the use of a novel fluorescence-labeled ligand. Phytomedicine Plus 100320. doi: 10.1016/j.phyplu.2022.100320
  • Meurer F.; Schulte-Michels J., Häberlein H. and Franken S. (2021) Iva leaves dry extract EA 575 mediates biased ß2-adrenergic receptor signaling. Phytomedicine in press.
  • Meurer F., Häberlein H. und Franken S. (2021) Der Efeublätter-Trockenextrakt EA 575 inhibiert den Adenosinrezeptor A2B-induzierten cAMP-Anstieg. Z Phytother 42, S23.
  • Dillenburger B., Kolb C. und Häberlein H. (2020) Aktueller Forschungsstand zum pflanzlichen Antidepressivum Johanniskraut. Nervenheilkunde 39, 565-571.
  • Bussmann H., Schulte-Michels J., Bingel M., Meurer F., Aatz S., Häberlein F., Franken S., and Häberlein H. (2020) A comparative study on the influence of an ivy and an ivy/thyme combination on the ß2-adrenergic signal transduction, Heliyon, e03960.
  • Keksel C., Bussmann H., Unger M., Drewe J., Boonen G., Häberlein H., and Franken S. (2019) St John´s wort extract influences membrane fluidity and composition of phosphatidylcholine and phosphatidylethanolamine in rat C6 glioblastoma cells, Phytomedicine 54, 66-76.
  • Schulte-Michels J., Keksel C., Häberlein H., and Franken S. (2018) Anti-inflammatory effects of ivy leaves dry extract: influence on transcriptional activity of NFkB, Immunopharmacology
  • Schulte-Michels J., Runkel F., Gokorsch S. and Häberlein H. (2016) Ivy leaves dry extract EA 575 decreases LPS-induced IL-6 release from murine macrophages, Pharmazie, 71, 158-161.
  • Schulte-Michels J., Wolf A., Aatz S., Engelhard K., Sieben A., Martinez-Osuna M., Häberlein F. and Häberlein H. (2016) α-Hederin inhibits G protein-coupled receptor kinase 2-mediated phosphorylation of β2-adrenergic receptors, Phytomedicine 23, 52-57.
  • Greunke C., Hage-Hülsmann A., Sorkalla T., Keksel N., Häberlein F. and Häberlein H. (2015) A systematic study on the influence of the main ingredients of an ivy leaves dry extract on the β2-adrenergic responsiveness of human airway smooth muscle cells, Pulm. Pharmacol. Ther. 31, 92-98
  • Jakobs, D., Hage-Hülsmann, A., Prenner, L., Kolb, C., Weiser, D., and Häberlein, H. (2013) Downregulation of ß1-adrenergic receptors in rat C6 glioblastoma cells by hyperforin and hyperoside from St Johns wort, J. Pharm. Pharmacol. 65(6), 907-915
  • De La Torre, D., Gordon, E.A., Digman, M.A., Stakic, M., Häberlein, H., Gratton, E., and Caballero-George, C. (2013) Raster image correlation spectroscopy in live cells expressing endothelin ETA receptor, Curr. Trends Biotechnol. Pharm. 7(1), 499-502.
  • Deutschmann, A., Hans, M., Meyer, R., Häberlein H.,
    and Swandulla D. (2013) Bisphenol A  inhibits voltage-activated Ca2+ channels in vitro: mechanisms and structural requirements, Mol. Pharmacol. 83, 501-511
  • Jakobs, D., Sorkalla, T., and Häberlein, H. (2012) Ligands for fluorescence correlation spectroscopy on G protein-coupled receptors, Curr. Med. Chem. 19(28), 4722-4730.
  • Caballero-George, C., Sorkalla, T., Jakobs, D., Bolanos, J., Raja, H., Shearer, C., Bermingham, E., and Häberlein, H. (2012) Fluorescence correlation spectroscopy in drug discovery: Study of Alexa532-endothelin 1 binding to the endothelin ETA receptor to describe the pharmacological profile of natural products, ScientificWorldJournal, doi: 10.1100/2012/524169
  • Sieben, A., Kaminski, T., Kubitscheck, U., and Häberlein, H. (2011) Terbutaline causes immobilization of single β2-adrenergic receptor-ligand complexes in the plasma membrane of living A549 cells as revealed by single-molecule microscopy, J. Biomed. Opt. 16, 026013 (Feb 25); doi:10.1117/1.3540670
  • Wolf, A., Gosens, R., Meurs, H., and Häberlein, H. (2011) Pre-treatment with α-hederin increases β-adrenoceptor mediated relaxation of airway smooth muscle, Phytomedicine 18, 214-218.
  • Veith, R., Sorkalla, T., Baumgart, E., Anzt, J., Häberlein, H, Tyagi, S., Siebrasse, J.P., and Kubitscheck, U. (2010) Balbiani ring mRNPs diffuse through and bind to clusters of large intranuclear molecular structures, Biophys J  99, 2676-2685.
  • Sieben, A., Prenner, L., Sorkalla, T., Wolf, A., Jakobs, D., Runkel, F., and Häberlein, H. (2009) α-hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of β2-adrenergic receptors, Biochemistry 48, 3477-3482.
  • Kappler, J., Hegener, O., Baader, S. L., Franken, S., Gieselmann, V., Häberlein, H., and Rauch, U. (2009) Transport of a hyaluronan-binding protein in brain tissue, Matrix Biol 28, 396-405.
  • Yaghootfam, A., Sorkalla, T., Häberlein, H., Gieselmann, V., Kappler, J., and Eckhardt, M. (2007) Cerebroside sulfotransferase forms homodimers in living cells, Biochemistry 46, 9260-9269.
  • Prenner, L., Sieben, A., Zeller, K., Weiser, D., and Häberlein, H. (2007) Reduction of high-affinity β2-adrenergic receptor binding by hyperforin and hyperoside on rat C6 glioblastoma cells measured by fluorescence correlation spectroscopy, Biochemistry 46, 5106-5113.
  •  Meissner, O., and Häberlein, H. (2006) Influence of xanthohumol on the binding behavior of GABAA receptors and their lateral mobility at hippocampal neurons, Planta Med 72, 656-658.
  • Meissner, O., and Häberlein, H. (2005) HPLC analysis of flavokavins and kavapyrones from Piper methysticum Forst, J Chromatogr B Analyt Technol Biomed Life Sci 826, 46-49.
  • Abouzied, M. M., El-Tahir, H. M., Prenner, L., Häberlein, H., Gieselmann, V., and Franken, S. (2005) Hepatoma-derived growth factor. Significance of amino acid residues 81-100 in cell surface interaction and proliferative activity, J Biol Chem 280, 10945-10954.
  • Hegener, O., Prenner, L., Runkel, F., Baader, S. L., Kappler, J., and Häberlein, H. (2004) Dynamics of β2-adrenergic receptor-ligand complexes on living cells, Biochemistry 43, 6190-6199.
  • Hegener, O., Jordan, R., and Häberlein, H. (2004) Dye-labeled benzodiazepines: development of small ligands for receptor binding studies using fluorescence correlation spectroscopy, J Med Chem 47, 3600-3605.
  • Bracher, F., Hildebrand, D., and Häberlein, H. (2004) 1-Substituted β-carboline-3-carboxylates with high affinities to the benzodiazepine recognition site, Nat Prod Res 18, 391-396.