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Sie sind hier: Startseite Lehre Neuroscience Seminar

Seminar

  • 19.12.2018 Alzheimer 3D-Model
    Speaker:  Barakat; Raghu
    ; Tutor: Walter
    Paper 1:
    Se Hoon Choi et al. (2014) A three-dimensional human neural cell culture
    model of Alzheimer’s disease. Nature 515:274-278
    Review 1:
    Steiner et al. (2008) Intramembrane proteolysis by g-secretase. J Biol Chem 283:29627-29631.
    Review 2:
    Haass and Selkoe (2007) Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid b-peptide. Nat Rev Mol Cell Biol 8:101-112.
  • Speaker: Abid, Hollowell  ; Tutor: Thelen
    Paper 1: Lee et al. (2010) Molecular characterization of mutations that cause globoid cell leukodystrophy and pharmacological rescue using small molecule chemical chaperones.  J. Neuroscience 30:5489-5497.
    Review 1:  Suzuki (2010) Globoid Cell Leukodystrophy (Krabbe´s Disease): Update.
    J. Child Neurol (2003) 18/595-603.
  • Speaker: Früngel, Kiani  ; Tutor: Matzner
    Paper 1: Komatsu et al. (2006) Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 441/880-884.
    Paper 2:Hara et al. (2006) Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441/885-889.
    Review 1:  Wong & Cuervo (2010) Autophagy gone awry in neurodegenrative diseases. Nature Neuroscience  13/805-811.
  • 10.01.2019  Cyclic nucleotide phosphodiesterase and myelin basic protein 
    Speaker:  Jung, Gschossmann ; Tutor: Eckhardt
    Paper 1:
    Snaidero et al. (2017) Antagonistic Functions of MBP and CNP Establish
    Cytosolic Channels in CNS Myelin. Cell Reports 18, 314–323
    Review 1:
    Raasakka and Kursula (2014) The myelin membrane-associated enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase: on a highway to structure and function. Neurosci Bull December 1, 2014, 30(6): 956–966
  • Speaker: Jin, Tennie ;  Tutor: Völker
    Paper 1:
    Southwood et al. (2002) The unfolded protein response modulates disease severity in Pelizaeus-Merzbacher disease. Neuron 36:585-596.
    Review 1:
    Lin and Popko (2009) ER stress in disorders of myelinating cells. Nat Neurosci 12:379-385.
    Review 2:
    Malhotra and Kaufman (2007) The ER and the unfolded protein response. Semin Cell Dev Biol 18:716-731.
  • Speaker:  Waris, Oh  ;  Tutor: Kunz
    Paper 1:
    Gautier, Kitada and Shen (2008) Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress. PNAS 105:11364-11369.
    Review 1:
    Mattson, Gleichmann and Cheng (2008) Mitochondria in neuroplasticity. and neurological disordsers. Neuron 30:748-766.
  • 15.01.2019  Neurotrophins
    Speaker: Lülsberg, Kuru   ; Tutor: Kunz
    Paper 1:
    Wu et al. Local translation of RhoA regulates growth cone
    collapse. Nature 436:1020-1024
    NATURE
    |
    Vol 436
    |
    18 August 2005
    Review 1: Lin & Holt, EMBO Member’s Review: Local translation and directional steering in axons. EMBO J. (2007) 26, 3729–3736
  • 16.01.2019  Huntington Disease
    Speaker:   Atanelov ; Tutor: Völker
    Paper 1:
    Banez-Coronel et al. (2015) RAN Translation in Huntington Disease. Neuron 88, 667–677
    NATURE
    |
    Vol 436
    |
    18 August 2005
    Review 1: Bates et al. (2015) Huntington Disease. Disease Primer 1, 1-23
  • 16.01.2019  SNARE mediated synaptic vesicle fusion
    Speaker:  Cunningham ;  Tutor: Matzner
    Paper 1:
    Mima et al. (2008) Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones. EMBO J 27:2031-2042.
    Paper 2:
    Takamori et al. (2006) Molecular anatomy of a trafficking organelle. Cell 127:831-846.
    Review 1:
    Rizo and Rosenmund (2008) Synaptic vesicle fusion. Nat Struct Mol Biol 15:665-674.
  • Speaker:  Paus  ; Tutor: Schoch
    Paper 1:
    Giuseppe Condomitti et al. (2018) An Input-Specific Orphan Receptor
    GPR158-HSPG Interaction Organizes Hippocampal Mossy Fiber-CA3 Synapses. Neuron 100, 1–15

 

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