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You are here: Home Research Group Gieselmann Group Matzner Publications


Publications of group Matzner since 2004


  • Schröder S, Matthes F, Hyden P, Andersson C, Fogh J, Müller-Loennies S, Braulke T, Gieselmann V, Matzner U. (2010) Site-specific analysis of N-linked oligosaccharides of recombinant lysosomal arylsulfatase A produced in different cell lines. Glycobiology 20, 248-259.


  • Matzner, U., Breiden, B., Schwarzmann, G., Yaghootfam, A., Fluharty, AL., Hasilik, A., Sandhoff, K., Gieselmann, V. (2009) Saposin B-dependent reconstitution of arylsulfatase A activity in vitro and in cell culture models of metachromatic leukodystrophy. J. Biol. Chem., 284, 9372-9381.


  • Matzner U, Lüllmann-Rauch R, Stroobants S, Andersson C, Weigelt C, Eistrup C, Fogh J, D'Hooge R, Gieselmann V (2009) Enzyme replacement improves ataxic gait and central nervous system histopathology in a mouse model of metachromatic leukodystrophy. Mol Ther., 17, 600-606.


  • Klein D, Yaghootfam A, Matzner U, Koch B, Braulke T, Gieselmann V. (2009) Mannose 6-phosphate receptor-dependent endocytosis of lysosomal enzymes is increased in sulfatide-storing kidney cells. Biol Chem., 390, 41-48.Matzner, U., Matthes, F., Weigelt, C., Andersson, C., Eistrup, C., Fogh, J., Gieselmann, V.


  • (2008) Non-inhibitory antibodies impede lysosomal storage reduction during enzyme replacement therapy of a lysosomal storage disease. J. Mol. Med., 86, 433-442.


  • Matzner, U., Matthes, F., Herbst, E., Lüllmann-Rauch, R., Callaerts-Vegh, Z., D'Hooge, R., Weigelt, C., Eistrup, C., Fogh, J. and Gieselmann, V. (2007) Induction of tolerance to human arylsulfatase A in a mouse model of metachromatic leukodystrophy. Mol. Med., 13, 471-479.


  • Franken, S., Wittke, D., Mansson, J.E., D'Hooge, R., De Deyn, P.P., Lullmann-Rauch, R., Matzner, U., Gieselmann, V. (2006): Modest phenotypic improvements in ASA-deficient mice with only one UDP-galactose:ceramide-galactosyltransferase gene. Lipids Health Dis. 5, 21-27.


  • Rickert, A.M., Ballvora, A., Matzner, U., Klemm, M. and Gebhardt, C. (2005): Quantitative genotyping of single nucleotide polymorphisms by allele-specific oligonucleotide hybridization on DNA microarrays. Biotechnol. Appl. Biochem., 42 (Pt 1), 93-96.


  • Matzner, U., Herbst, E., Hedayati, K.K., Lullmann-Rauch, R., Wessig, C., Schroder, S., Eistrup, C., Moller, C., Fogh, J. and Gieselmann, V. (2005): Enzyme replacement improves nervous system pathology and function in a mouse model for metachromatic leukodystrophy. Hum. Mol. Genet. 14, 1139-1152.


  • Matzner, U. and Gieselmann, V. (2005): Gene therapy of metachromatic leukodystrophy. Expert Opin. Biol. Ther., 5, 55-65.


  • Matzner, U. (2005) Therapy of lysosomal storage diseases. In Lysosomes, Saftig, P. editor. LandesBioscience, Georgetown (TX), U.S.A; ISBN 1-58706-286-0


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