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Publications

Journal Articles

2014

  • Singh, S.*, Winter, D.*, Kirchner, M.*, Chauchan, R.*, Ahmed, S., Uzlu, N., Tzur, A., Steen, J.A., Steen, H., Co-regulation proteomics reveals substrates and mechanisms of APC/C dependent degradation. EMBO Journal, 2014, 33(4), 385-399, *shared first authors. PubMed PMID: 24510915

2013

  • Eichhorn T., Winter D., Büchele B., Dirdjaja N., Frank M., Lehmann W.D., Mertens R., Krauth-Siegel R.L., Simmet T., Granzin J., Efferth T., Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum.B iochem Pharmacol., 2013, 85, 38-45. PubMed PMID: 23085438

2012

  •  Winter, D., Hung, C.W., Jaskolla, T.W., Karas, M., Lehmann, W.D., Enzyme-cleavable Tandem Peptides for Quantitative Studies in Mass Spectrometry-Based Proteomics, Proteomics, 2012, 12, 3470-3474. PubMed PMID:  23090848
  • Renard B.Y., Xu B., Kirchner M., Zickmann F., Winter D., Korten S., Brattig N.W., Tzur A., Hamprecht F.A., Steen H., Overcoming species boundaries in peptide identification with BICEPS. Mol Cell Proteomics, 2012, 11. PubMed PMID: 22493179
  • Singh, S., Winter, D., Bilimoria, P., Bonni, A., Steen, H., Steen, J., FLEXIQinase: A Novel High Resolution, Next Generation Kinase Assay. Nature Methods, 2012, 9, 504-508PubMed PMID: 22484849
  • Weeraratne S.D., Amani V., Teider N., Pierre-Francois J., Winter D., Kye M.J., Sengupta S., Archer T., Remke M., Bai A.H., Warren P., Pfister S.M., Steen J.A., Pomeroy S.L., Cho Y.J., Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma.Acta Neuropath ol. 2012 Apr;123(4):539-552. PubMed PMID: 22402744

2011

  • Wang, X., Winter, D., Ashrafi, G., Schlehe, J., Wong, Y.L., Selkoe, D., Rice, S., Steen, J., Lavoie, M.J., Schwarz, T.L., PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility. Cell 2011, 147, 893-906.PubMed PMID: 22078885
  • Winter, D., Steen, H., Optimization of Cell Lysis and Protein Digestion Protocols for the Analysis of HeLa S3 Cells by LC-MS/MS.PROTEOMICS, 2011, 11, 4726-4730. PubMed PMID: 22002805
  • Seidler, J., Zinn, N., Haaf, E., Boehm, M. E., Winter, D., Schlosser, A., Lehmann, W.D., Metal ion-mobilizing additives for comprehensive detection of femtomole amounts ofphosphopepti des by reversed phase LC-MSAmino Acids 2011, 41, 311-320. PubMed PMID: 20552382

2010

  • Zinn, N., Winter, D., Lehmann, W. D., Recombinant isotope labeled and selenium quantified proteins for absolute protein quantification. Analytical Chemistry 2010, 82, 2334-2340. PubMed PMID: 20163147
  • Winter, D., Seidler, J., Kugelstadt, D., Derrer, B., Kappes, B., Lehmann, W.D., Minimally permutated peptide analogs as internal standards for relative and absolute quantification of peptides and proteins. PROTEOMICS 2010, 10, 1510-1514.PubMed PMID: 20104620
  • Winter, D., Seidler, J., Hahn, B., Lehmann, W. D., Structural and Mechanistic Information on c(1) Ion Formation in Collision-Induced Fragmentation of Peptides. J. Am. Soc. Mass Spectrom. 2010, 21, 1814-1820. PubMed PMID: 20688526

2009

  • Winter, D., Seidler, J., Ziv-Lehrman, S., Shiloh, Y., Lehmann, W. D., Simultaneous Identification and Quantification of Proteins by Differential O-16/O-18 Labeling and UPLC-MS/MS Applied to Mouse Cerebellar Phosphoproteome Following Irradiation. Anticancer Research 2009, 29, 4949-4958. PubMed PMID: 20044601
  • Winter, D., Seidler, J., Ziv, Y., Shiloh, Y., Lehmann, W. D., Citrate Boosts the Performance of Phosphopeptide Analysis by UPLC-ESI-MS/MS. Journal of Proteome Research 2009, 8, 418-424. PubMed PMID: 19053530
  • Winter, D.Pipkorn, R., Lehmann,W. D.,Separa tion of peptide isomers and conformers by ultra performance liquid chromatography.Journal of Separation Science 2009, 32, 1111-1119. PubMed PMID: 19360781
  • Winter, D., Lehmann, W. D., Sequencing of the thirteen structurally isomeric quartets of N-terminal dipeptide motifs in peptides by collision-induced dissociation. PROTEOMICS 2009, 9, 2076-2084. PubMed PMID: 19322779
  • Winter, D., Lehmann, W. D., Individual b(2) ion fragmentation profiles combined with AspN digestion improve N-terminal peptide sequencing.Anal. Bioanal. Chem . 2009,393 , 1587-1591. PubMed PMID: 19214481
  • Winter, D., Kugelstadt, D., Seidler, J., Kappes, B., Lehmann, W. D., Protein phosphorylation influences proteolytic cleavage and kinase substrate properties exemplified by analysis of in vitro phosphorylated Plasmodium falciparumglideosome-associated protein 45 by nano-ultra performance liquid chromatography-tandem mass spectrometry. Analytical Biochemistry 2009, 393, 41-47. PubMed PMID: 19549500
  • Schilling, M., Maiwald, T., Hengl, S., Winter, D., Kreutz, C., Kolch, W., Lehmann, W.D., Timmer, J., Klingmüller, U., Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions. Molecular Systems Biology 2009, 5, 334. PubMed PMID: 20029368
  • Renard, B. Y., Kirchner, M., Monigatti, F., Ivanov, A. R., Rappsilber, J., Winter, D., Steen, J., Hamprecht, F.A., Steen, H., When less can yield more - Computational preprocessing of MS/MS spectra for peptide identification. PROTEOMICS 2009, 9, 4978-4984. PubMed PMID: 19743429
  • Brenner, D., Brechmann, M., Rohling, S., Tapernoux, M., Mock, T., Winter, D., Lehmann, W.D., Kiefer, F., Thome, M., Krammer, P.H., Arnold, R., Phosphorylation of CARMA1 by HPK1 is critical for NF-kappa B activation in T cellsProc. Natl. Acad. Sci. U. S. A. 2009, 106, 14508-14513. PubMed PMID: 19706536

2008

  • Winter, D., Shiloh, Y., Lehmann, W. D., Phosphopeptide Isomer Analysis by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry. AL On-Line 2008, June 2008, 21-24. PubMed PMID:  19931354

2007

  • Kugelstadt, D., Winter, D., Pluckhahn, K., Lehmann, W. D., Kappes, B., Raf kinase inhibitor protein affects activity of Plasmodium falciparum calcium-dependent protein kinase 1. Mol. Biochem. Parasitol. 2007, 151, 111-117. PubMed PMID:  17123645

Patents

  • European Patent EP20080786120Winter, D., Lehmann, W. D., Method for determining the concentration of a molecule.
  • US Patent US 8,044,345 B2Winter, D., Lehmann, W. D., Method for determining the concentration of a molecule.

 

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